Monday, 15th September International Association for Breast Cancer Research 2014

• Methylome sequencing reveals distinct methylation clusters associated with breast cancer - Susan Clark
• Breast cancer susceptibility: From GWAS hit to target gene - Georgia Chenevix-Trench
• Molecular complexity of breast cancer - Katherine Hoadley
• Specification and maintenance of mammary epithelial cells by the Polycomb Repressive Complex 2 family - Ewa M. Michalak

• Tracking breast epithelial cells in vivo - Jane Visvader
• Cell division in the mammary epithelium - John Stingl
• Regulation of stem cells by paracrine and microenvironmental influences - Rama Khokha
• ­Rspo1 Is A Novel Hormone Mediator for Mammary Stem Cell Self-renewal - Arial Y. Zeng

This is an open lecture, the public are welcome to attend 

This session will include the following panelists views on the future of breast cancer research and therapy:

Katherine Hoadley, Lineberger Comprehensive Cancer Centre, UNC, Chapel Hill

Geoff Lindeman, Walter and Eliza Hall Institute, Melbourne

Joe Gray, Helen Diller Comprehensive Cancer Centre UCSF, Lawrence Livermore Laboratory and the Oregon Health and Science University

Nancy Hynes, Friedrich Miescher Institute for Biomedical Research, Basel

Jason Carroll, Cancer Research UK, Cambridge Institute, University of Cambridge

Sally Crossing, Cancer Voices, Australia

Audience Q&A: The future of breast cancer research therapy

• Multiple molecular subtypes of triple negative breast cancer depend on androgen receptor for proliferation and invasion - Valerie Barton
• Incidence of c-MET gene amplification and protein expression in triple negative breast cancer patients, and correlation to clinicopathological features  - Rhiannon Beckers
• Regulation of ABCG2 expression and function in breast cancer cells - Jacqueline Bentel
• The myotubularin-related protein 4 (Mtmr4) PI(3)P 3-phosphatase regulates breast cancer growth and metastasis  - Micka Bertucci
• Targeting glucose metabolism - a strategy for overcoming drug resistance in breast cancer - Anneke C. Blackburn
• Polymorphisms in Cyp2r1 and disruption of the vitamin D pathway associate with the SuprMam1 breast cancer susceptibility locus in mice - Anneke C. Blackburn
• Rab coupling proteins is a critical regulator of ErbB2-mediated breast cancer tumorigenesis and metastasis - Pierre-Luc Boulay
• The important role of chemokine receptor CCR7 in regulation of breast cancer stem cells - Sarah T. Boyle
• Parity does not reduce short-term mammary stem cell activity, but the methods used to assess this reveal an estrogen responsive stem/progenitor subset  - Kara Britt
• Gwl-Cdk1-PP2A axis as the ultimate controller of mitotic exit and chromosome instability - Andrew Burgess
• Novel approaches to targeting the tumour-stroma coalition in triple negative breast cancers - Aurélie Cazet
• STC1 expression is associated with tumour growth and metastasis in breast cancer - Andy Chang
• Novel serum protein biomarker panel predicts disease-free survival in patients with ER-negative breast cancer - Liping Chung
• Pomegranate and the breast cancer stem cells - a detailed study about their link and a novelnutraceutical therapy - Christina Edward
• Brisbane Breast Bank - Kaltin Ferguson
• Molecular analysis of Circulating Tumor Cells (CTCs) from the blood of patients with solid cancers - Christin Gasch
• Targets of microRNAs involved in radiation response are promising biomarkers in silico - Harriet E. Gee
• Targeting the nuclear receptor superfamily for treatment and prognosis in breast cancer - Dinny Graham
• Pubertal high fat diet: A peri-pubertal window for susceptibility and a unique expression signature for tumors - Sandra Haslam
• ER and PR are functionally non-overlapping in normal breast but converge in breast cancer - Heidi N. Hilton
•   A novel in vivo model of tumour cell migration and dormancy in zebrafish - Georgina Hollway
• Nerve fibres in the microenvironment of breast cancer: An underestimated feature related to tumour aggressiveness - Hubert Hondermarck
• Cancer stem cell expressions in primary and metastatic breast cancer - Yoshiya Horimoto
• Targeting the Hedgehog signalling pathway in triple negative breast cancer - Mun Hui
• Recapitulating the adult mammary gland stem cell and cancer stem cell niche in vitro using 3D engineered matrices - Rob Hume
• Spontaneous epigenetic changes in human mammary epithelial cells induce rapid proliferation and are associated with increased levels of wild-type p53 - Lily I. Huschtscha
• The association between aldehyde dehydrogenase 1 positive cells and breast cancer risk may be unrelated to stemness - Bjorn L. Isfoss
• Improving the efficacy of monoclonal antibody therapies for the treatment of breast cancer - Shannon R. Joseph
• △40P53 regulation of ERα-mediated signalling in breast cancer - Kelly A. Avery-Kiejda
• Outcomes in postmenopausal women with hormone receptor positive, HER-2 negative T2N0 breast cancer without adjuvant chemotherapy - Yoo Seok Kim
• CXCR4 and CCR7 interact to form a functional dimeric receptor and to promote cancer metastasis - Marina Kochetkova
• Rigid reconstruction of the chest wall after sternectomy and modified radical mastectomy - Beatrice, Fang Ju Koh
• Breast cancer metastasis to gynaecological organs: Impacting young women diagnosed with a luminal tumour subtype - Jamie Kutasovic
• WBP2 at the crossroad of Wnt and Hippo signalling pathways in triple negative breast cancer - Yoon Pin Lim
• Sensitization of breast cancer cells to DNA-damaging therapies by targeting insulin-like growth factor binding protein-3 signalling - Mike Z. Lin
• Molecular mechanisms by which P-Rex1 acts as an oncogene in breast cancer - Heng-Jia (Tina) Liu
• Coordinated epigenetic change occurs during early breast carcinogenesis - Warwick J. Locke
• Replication study of genome-wide significant mammographic density SNPs in Asian women - Shivaani Mariapun
• The Australian Breast Cancer Tissue Bank: A core resource for translational research - Jane E. Carpenter
• The role of specific BARD1 splice variant isoforms in breast cancer cell resistance to DNA damaging agents - Kamila A. Marzec
• Mammographic density and breast cancer risk by family history in women of white and Asian ancestry - Gertraud Maskarinec
• Integrative molecular profiling of invasive lobular carcinoma - Amy McCart Reed
• Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate both ZNF365 and NRBF2 - Karen McCue
• Direct visualisation of mRNA transcripts in breast cancer - Katie Meehan
• Identifying downstream targets of the transcription factor ELF5 that mediate anti-oestrogen resistance in breast cancer - Stephanie Allerdice

• Understanding estrogen receptor transcription in breast cancer - Jason S. Carroll
• Genomic actions of androgen receptor in breast cancer - Wayne Tilley
• Understanding and targeting acquired ESR1 mutations in hormone resistant breast cancers - Geoffrey Greene