Breast Cancer Stem Cell is a single, genetically abnormal cell. As this one culprit cell divides, it eventually becomes a tumor and develops a blood supply to nourish its continued growth. The target should be the cancer stem cells and not any normal cells.
The most common sign of breast cancer is a new lump or mass.
Most often when untreated a breast cancer stem cells trigger the cancer growth to spread to underarm
lymph nodes even before the original tumor in the breast tissue is large enough to be detected. We are
in need of a therapy/treatment to selectively kill cancer stem cells at the original tumor site and in
distant metastases with no toxic effects on healthy cells, including normal stem cells. Cancer stem cells
are critical to a cancer's ability to recur following conventional chemotherapies and radiation therapy
because they can quickly multiply and establish new tumors that are often therapy resistant. Here comes
the role of pomegranate which has a long history of use as a food and medicine in Asia and South
America. According to the WHO, this medicinal plant is the best source to obtain variety of drugs. About
80% of individuals from developed countries use them in traditional medicine. The plant part or the
compounds derived from the plants are now established recipe of both pharmaceuticals and
nutraceuticals. There are many evidences that the pomegranate has good anti-cancer properties against
prostate, bowel and liver cancer. But there are no studies so far looking at the use of pomegranate in
humans. The objective of this paper is to provide a detailed report about why pomegranate in human
breast cancer, scientific research proof for the medicinal quality of pomegranate, Sensitivity of
Pomegranate and its hypersensitive reactions, its interactions with drugs and a novel nutraceutical
therapy using pomegranate.